Sabrina Bochicchio

Sabrina Bochicchio

Assegnista di ricerca

telephone +39.089.968291

mail sbochicchio@unisa.it

CV CV completo (richiedi la password via email)

researchgatelinkedin

Curriculum Accademico

Sabrina Bochicchio si è laureata in Biotecnologie Molecolari, nell’A.A. 2010/11, presso il Dipartimento di Biologia, Difesa e Biotecnologie Agro-Forestali dell’Università degli Studi della Basilicata con una tesi dal titolo “Effetto dello stress alcolico su Oenococcus oeni” in cui ha valutato le condizioni ottimali e i punti critici nell’utilizzo di colture starter per l’ottimizzazione della fermentazione malolattica nei vini. Nel 2012 ha svolto una collaborazione volontaria presso i laboratori di ricerca dell’ Istituto di Ricovero e Cura a Carattere Scientifico IRCCS CROB in Rionero in Vulture (Pz) occupandosi dello studio dell’espressione di microRNA in plasmacellule di pazienti affetti da Mieloma Multiplo e del ruolo di Lin28 nelle leukemia stem cells. Nel 2013 ha usufruito di una borsa di studio presso il dipartimento di Ingegneria Industriale e Farmacia dell’Università degli Studi di Salerno dove, dal 2014, è dottoranda in Ingegneria Industriale – Ingegneria Chimica con un progetto dal titolo “Nanostructured vectors for the transport of active molecules through biological membranes for pharmaceutical and nutraceutical applications”. L’attività di ricerca della Dott.ssa Sabrina Bochicchio si svolge presso i laboratori del gruppo TPP (www.minerva.unisa.it) dell’Università di Salerno e prevede lo sviluppo di nuove tecniche per l’incapsulamento di molecole attive in micro e nano vettori. Il suo lavoro è focalizzato sulla produzione di liposomi come drug carrier systems, mediante l’utilizzo di una tecnica assistita da ultrasuoni; sul processo che porta alla produzione di liposomi cationici, funzionalizzati, per l’incapsulamento di siRNA e di liposomi neutri come vettori di molecole terapeutiche di diversa natura; su studi di rilascio degli agenti terapeutici incapsulati nei sistemi vescicolari prodotti. Ha partecipato come cultore della materia alle commissioni d’esame nell’anno accademico 2012/2013 dei corsi di Rilascio e direzionamento dei farmaci e di Analisi dei prodotti cosmetici. Ha inoltre effettuato tutoraggio per lo svolgimento di 1 tesi di laurea in Ingegneria Chimica. Ha prodotto 8 lavori di cui 2 sono pubblicazioni su rivista internazionale; 4 sono comunicazioni a convegni internazionali e 2 sono comunicazioni a convegni nazionali.

Tesi

Tesi di dottorato di ricerca

  • Sabrina Bochicchio, Nanostructured vectors for the transport of active molecules through biological membranes for pharmaceutical and nutraceutical applications, Dottorato di ricerca in Ingegneria Industriale, Relatori: Prof. Ing. Anna Angela Barba, Comitato scientifico: Prof. Sotiris Missailidis (Instituto Oswaldo Cruz, Brasil, Open University, UK), Prof. Gabriele Grassi (University Hospital of Cattinara, Trieste), Prof. Gaetano Lamberti (Università degli Studi di Salerno

Pubblicazioni

2021

Bochicchio, Sabrina; Lamberti, Gaetano; Barba, Anna Angela

Polymer–Lipid Pharmaceutical Nanocarriers: Innovations by New Formulations and Production Technologies Journal Article

In: Pharmaceutics, vol. 13(2), no 198, pp. 15, 2021, ISSN: 19994923.

Abstract | Links | BibTeX | Tags: drug delivery, hybrid nanoparticles, lipids, nanotechnologies, polymers, production technologies

2020

Simone, Veronica De; Dalmoro, Annalisa; Bochicchio, Sabrina; Caccavo, Diego; Lamberti, Gaetano; Bertoncin, Paolo; Barba, Anna Angela

Nanoliposomes in polymeric granules: Novel process strategy to produce stable and versatile delivery systems Journal Article

In: Journal of Drug Delivery Science and Technology, vol. 59, pp. 7, 2020.

Abstract | Links | BibTeX | Tags: Compressibility index, Lipid-polymeric, Simil-microfluidic method, Texture analyses, Wet granulation

Bochicchio, Sabrina; Dalmoro, Annalisa; Lamberti, Gaetano; Barba, Anna Angela

Advances in Nanoliposomes Production for Ferrous Sulfate Delivery Journal Article

In: Pharmaceutics, vol. 12, no 5, pp. 445, 2020.

Abstract | Links | BibTeX | Tags: drug delivery, ferrous sulfate, nanoliposome, simil-microfluidic apparatus, sonication

Bochicchio, Sabrina; Dalmoro, Annalisa; Simone, Veronica De; Bertoncin, Paolo; Lamberti, Gaetano; Barba, Anna Angela

Simil-Microfluidic Nanotechnology in Manufacturing of Liposomes as Hydrophobic Antioxidants Skin Release Systems Journal Article

In: Cosmetics, vol. 7, no 22, pp. 13, 2020.

Abstract | Links | BibTeX | Tags: antioxidants, cosmeceutics, nanoliposomes, simil-microfluidic technology, transdermal delivery

Barba, Anna Angela; Dalmoro, Annalisa; Bochicchio, Sabrina; Simone, Veronica De; Caccavo, Diego; Iannone, Marco; Lamberti, Gaetano

Engineering approaches for drug delivery systems production and characterization Journal Article

In: International Journal of Pharmaceutics, 2020.

Abstract | Links | BibTeX | Tags: drug delivery, Hydrogel, Innovation in Europe, Microvectors, Modeling, Nanovectors

2019

Barba, Anna Angela; Bochicchio, Sabrina; Dalmoro, Annalisa; Caccavo, Diego; Cascone, Sara; Lamberti, Gaetano

Polymeric and lipid-based systems for controlled drug release: an engineering point of view Book Chapter

In: Grumezescu, Alexandru Mihai (Ed.): Chapter 10, pp. 267-304, Elsevier, 2019, ISBN: 978-0-12-816505-8.

Abstract | Links | BibTeX | Tags: characterization techniques, controlled release, lipid nanoparticles, Mathematical modeling, Polymer nanoparticles, production processes

Barba, Anna Angela; Bochicchio, Sabrina; Bertoncin, Paolo; Lamberti, Gaetano; Dalmoro, Annalisa

Coating of Nanolipid Structures by a Novel Simil-Microfluidic Technique: Experimental and Theoretical Approaches Journal Article

In: Coatings, vol. 9, no 491, pp. 1-15, 2019.

Abstract | Links | BibTeX | Tags: Chitosan, Coated nanoliposomes, Guar guam, Liposome bioadhesive, Liposomi bioadesivi, Muchoadesiveness, Simil-microfluidic technique

Barba, Anna Angela; Bochicchio, Sabrina; Dalmoro, Annalisa; Lamberti, Gaetano

Lipid Delivery Systems for Nucleic-Acid-Based-Drugs: From Production to Clinical Applications Journal Article

In: Pharmaceutics, vol. 11, no 360, 2019.

Abstract | Links | BibTeX | Tags: clinical trials, liposomes, Micro and Nano Vectors, NABDs, siRNA

Dalmoro, Annalisa; Bochicchio, Sabrina; Lamberti, Gaetano; Bertoncin, Paolo; Janssens, Barbara; Barba, Anna Angela

Micronutrients encapsulation in enhanced nanoliposomal carriers by a novel preparative technology Journal Article

In: RSC Advances, vol. 9, pp. 19800-19812, 2019.

Abstract | Links | BibTeX | Tags: Drug Delivery Systems, Micro and Nano Vectors

2018

Bochicchio, Sabrina; Dalmoro, Annalisa; Bertoncin, Paolo; Lamberti, Gaetano; Moustafine, Rouslan I.; Barba, Anna Angela

Design and production of hybrid nanoparticles with polymeric-lipid shell–core structures: conventional and next-generation approaches Journal Article

In: RSC Advances, vol. 8, pp. 34614–34624, 2018.

Abstract | Links | BibTeX | Tags: Micro and Nano Vectors

Dalmoro, Annalisa; Bochicchio, Sabrina; Nasibullin, Shamil F.; Bertoncin, Paolo; Lamberti, Gaetano; Barba, Anna Angela; Moustafine, Rouslan I.

Polymer-lipid hybrid nanoparticles as enhanced indomethacin delivery systems Journal Article

In: European Journal of Pharmaceutical Sciences, vol. 121, pp. 16-28, 2018.

Abstract | Links | BibTeX | Tags: Micro and Nano Vectors

2017

Bochicchio, Sabrina; Sala, Marina; Spensiero, Antonia; Scala, Maria Carmina; Gomez-Monterrey, Isabel; Lamberti, Gaetano; Barba, Anna Angela

On the design of tailored liposomes for KRX29 peptide delivery Journal Article

In: New Journal of Chemistry, vol. 41, no 19, pp. 11280-11290, 2017, ISSN: 1144-0546.

Abstract | Links | BibTeX | Tags: liposome, peptide

Bochicchio, Sabrina; Lamberti, Gaetano; Barba, Anna Angela

Phenomenological and Formulation Aspects in Tailored Nanoliposome Production Book Chapter

In: Liposomes, Chapter 2, IntechOpen, 2017.

Abstract | Links | BibTeX | Tags: cell‐mimetic system, gene therapy, liposome, nanoliposomes delivery systems, nutraceuticals, personalized carriers, simil‐microfluidic approach, ultrasonic size reduction

Bochicchio, Sabrina; Dalmoro, Annalisa; Recupido, Federica; Lamberti, Gaetano; Barba, Anna Angela

Nanoliposomes Production by a Protocol Based on a Simil-Microfluidic Approach Book Chapter

In: Piotto, Stefano; Rossi, Federico; Concilio, Simona; Reverchon, Ernesto; Cattaneo, Giuseppe (Ed.): Chapter 1, pp. 3-10, Springer International Publishing AG 2018, 2017, ISBN: 978-3-319-62026-8.

Abstract | Links | BibTeX | Tags: liposome

Bochicchio, Sabrina; Dapas, Barbara; Russo, Ilaria; Ciacci, Carolina; Piazza, Ornella; Smedt, Stefan De; Pottie, Eline; Barba, Anna Angela; Grassi, Gabriele

In vitro and ex vivo delivery of tailored siRNA-nanoliposomes for E2F1 silencing as a potential therapy for colorectal cancer Journal Article

In: International Journal of Pharmaceutics, vol. 525, no 2, pp. 377–387, 2017.

Abstract | Links | BibTeX | Tags: Micro and Nano Vectors

Piazza, Ornella; Russo, Ilaria; Bochicchio, Sabrina; Barba, Anna Angela; Lamberti, Gaetano; Zeppa, Pio; Crescenzo, Vincenzo Di; Carrizzo, Albino; Vecchione, Carmine; Ciacci, Carolina

Cyclin D1 gene silencing by siRNA in ex vivo human tissues cultures Journal Article

In: Current Drug Delivery, vol. 14, no 2, pp. 246 - 252, 2017.

Abstract | Links | BibTeX | Tags:

D'Apolito, Rosa; Bochicchio, Sabrina; Dalmoro, Annalisa; Barba, Anna Angela; Guido, Stefano; Tomaiuolo, Giovanna

Microfluidic investigation of the effect of liposome surface charge on drug delivery in microcirculation Journal Article

In: Current Drug Delivery, vol. 14, no 2, pp. 231 - 238, 2017.

Abstract | Links | BibTeX | Tags:

Bochicchio, Sabrina; Dalmoro, Annalisa; Barba, Anna Angela; D'Amore, Matteo; Lamberti, Gaetano

New preparative approaches for micro and nano drug delivery carriers Journal Article

In: Current Drug Delivery, vol. 14, no 2, pp. 203 - 215, 2017.

Abstract | Links | BibTeX | Tags: Micro and Nano Vectors

Dalmoro, Annalisa; Abrami, Michela; Galzerano, Barbara; Bochicchio, Sabrina; Barba, Anna Angela; Grassi, Mario; Larobina, Domenico

Injectable chitosan/b-glycerophosphate system for sustained release: gelation study, structural investigation and erosion tests Journal Article

In: Current Drug Delivery, vol. 14, no 2, pp. 216 - 223, 2017.

Abstract | Links | BibTeX | Tags: Hydrogel Characterization

2016

Bochicchio, Sabrina; Barba, Anna Angela; Grassi, Gabriele; Lamberti, Gaetano

Vitamin delivery: Carriers based on nanoliposomes produced via ultrasonic irradiation Journal Article

In: LWT - Food Science and Technology, vol. 69, pp. 9-16, 2016.

Abstract | Links | BibTeX | Tags: Micro and Nano Vectors

2015

Caccavo, Diego; Cascone, Sara; Bochicchio, Sabrina; Lamberti, Gaetano; Dalmoro, Annalisa; Barba, Anna Angela

Hydrogels-based matrices behavior: experimental and modeling description Proceedings Article

In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 2015.

BibTeX | Tags:

Dalmoro, Annalisa; Bochicchio, Sabrina; Lamberti, Gaetano; Sala, Marina; Campiglia, Pietro

Ultrasonic assisted production of nanoliposomes as peptide delivery vectors Proceedings Article

In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 2015.

BibTeX | Tags:

Bochicchio, Sabrina; Dalmoro, Annalisa; Cascone, Sara; Lamberti, Gaetano; Barba, Anna Angela

dsDNA encapsulating in nanoliposomal structures towards gene therapies Proceedings Article

In: 1st International Congress οf Controlled Release Society - Greek Local Chapter, 2015.

BibTeX | Tags:

2014

Dalmoro, Annalisa; Bochicchio, Sabrina; Apicella, Pietro; D'Amore, Matteo; Barba, Anna Angela

Micro and nano structured vectors for the drug delivery Proceedings Article

In: 21st International Congress of Chemical and Process Engineering CHISA 2014, 2014.

BibTeX | Tags:

Bochicchio, Sabrina; Dalmoro, Annalisa; Grassi, Gabriele; Lamberti, Gaetano; Barba, Anna Angela

Vectors for vitamins delivery: nano liposomes production via utrasonic irradiation Proceedings Article

In: 13th European Symposium on Controlled Drug Delivery, 2014.

BibTeX | Tags:

Dalmoro, Annalisa; Bochicchio, Sabrina; Lamberti, Gaetano; D'Amore, Matteo; Barba, Anna Angela

Vectors for vitamins delivery: shell-core microparticles production via ultrasonic atomization and microwave stabilization Proceedings Article

In: 13th European Symposium on Controlled Drug Delivery, 2014.

BibTeX | Tags:

Barba, Anna Angela; Bochicchio, Sabrina; Dalmoro, Annalisa; Lamberti, Gaetano

Liposomal SUVs preparation by ultrasonic energy: a new approach based on a conventional technique Proceedings Article

In: 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2014.

BibTeX | Tags:

Barba, Anna Angela; Bochicchio, Sabrina; Lamberti, Gaetano; Dalmoro, Annalisa

Ultrasonic energy in liposome production: process modelling and size calculation Journal Article

In: Soft Matter, vol. 10, no 15, pp. 2574, 2014, ISSN: 1744-683X.

Abstract | Links | BibTeX | Tags: Micro and Nano Vectors

Bochicchio, Sabrina; Dalmoro, Annalisa; Barba, Anna Angela; Grassi, Gabriele; Lamberti, Gaetano

Liposomes as siRNA Delivery Vectors Journal Article

In: Current drug metabolism, vol. 15, no 9, pp. 882–892, 2014, ISSN: 1389-2002.

Abstract | Links | BibTeX | Tags: Drug Delivery Systems, liposome, Micro and Nano Vectors, siRNA

2013

D'Amore, Matteo; Dalmoro, Annalisa; Bochicchio, Sabrina; Lamberti, Gaetano; Barba, Anna Angela

Produzione di sistemi di rilascio ottimali per i Nucleic Acid Based Drugs in terapie antitumorali Proceedings Article

In: Le Giornate del Farmaco, pp. 1–1, FISCIANO (SA), 2013.

BibTeX | Tags:

Barba, Anna Angela; Lamberti, Gaetano; Dalmoro, Annalisa; Bochicchio, Sabrina; D'Amore, Matteo

On new techniques to produce biocompatible micro and nano systems Proceedings Article

In: 1st Workshop on Bio-Nanomaterials, pp. 1–1, FISCIANO (SA) ITALY, 2013.

BibTeX | Tags: